2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-137983
    3-O-Acetylbetulin
    3-O-Acetylbetulin is a derivative of Betulin (HY-N0083), a sterol regulatory element-binding protein (SREBP) inhibitor. 3-O-Acetylbetulin can be utilized in synthesis of other betulin derivatives.
    3-O-Acetylbetulin
  • HY-W011340
    5-Hydroxy flunixin
    5-Hydroxy flunixin, the principal metabolite of Flunixin (HY-121046), retains the Flunixin's anti-inflammatory properties and plays a significant role in mitigating pain and inflammation in various veterinary applications. It assists in alleviating conditions such as colic in horses, musculoskeletal disorders, and infectious diseases in cattle, while also supporting the management of mastitis-metritis-agalactia syndrome in sows.
    5-Hydroxy flunixin
  • HY-W019773R
    Albendazole sulfone (Standard)
    Albendazole sulfone (Standard) is the analytical standard of Albendazole sulfone. This product is intended for research and analytical applications. Albendazole sulfone is a metabolite of Albendazole, and exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes.
    Albendazole sulfone (Standard)
  • HY-W013549R
    6-Aminopenicillanic acid (Standard)
    6-Aminopenicillanic acid (Standard) is the analytical standard of 6-Aminopenicillanic acid. This product is intended for research and analytical applications. 6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses.
    6-Aminopenicillanic acid (Standard)
  • HY-N8269
    Rivularin
    		98.13%
    Rivularin (Skullcapflavone) is a flavonoid that can be found in Radix scutellariae.
    Rivularin
  • HY-135384R
    tert-Buthyl Pitavastatin (Standard)
    Flavone (Standard) is the analytical standard of Flavone. This product is intended for research and analytical applications. Flavone is an endogenous metabolite.
    tert-Buthyl Pitavastatin (Standard)
  • HY-W710753
    D,L-Sulforaphane glutathione-d5
    D,L-Sulforaphane glutathione-d5 (DL-SFN-GSH-d5) is deuterium labeled DL-Sulforaphane glutathione. DL-Sulforaphane glutathione (DL-SFN-GSH) is a metabolite of Sulforaphane (HY-13755) in rat plasma.
    D,L-Sulforaphane glutathione-d<sub>5</sub>
  • HY-W561311
    M387783
    M387783 is an oxidative metabolite of Gefitinib (HY-50895). M387783 is commonly used in pharmacokinetic and metabolic pathway studies.
    M387783
  • HY-135180R
    1H-1-Ethyl Candesartan Cilexetil (Standard)
    1H-1-Ethyl Candesartan Cilexetil (Standard) is the analytical standard of 1H-1-Ethyl Candesartan Cilexetil. This product is intended for research and analytical applications. 1H-1-Ethyl Candesartan Cilexetil is a potential impurity found in bulk preparations of Candesartan Cilexetil (HY-17505).
    1H-1-Ethyl Candesartan Cilexetil (Standard)
  • HY-W753325
    α-Hydroxy flualprazolam
    		Control
    α-Hydroxy flualprazolam is a benzodiazepine.
    α-Hydroxy flualprazolam
  • HY-168774
    17(S)-HDoTE
    17(S)-HDoTE is a metabolite of Adrenic acid (HY-W013215). 17(S)-HDoTE is formed by the catalysis of Adrenic acid through 15-lipoxygenase (15-LO).
    17(S)-HDoTE
  • HY-W004412R
    Olanzapine-lactam (Standard)
    Olanzapine-lactam (Standard) is the analytical standard of Olanzapine-lactam. This product is intended for research and analytical applications. Olanzapine-lactam (LY301664) is a metabolite of Olanzapine (HY-14541).
    Olanzapine-lactam (Standard)
  • HY-103252S1
    Monomethyl fumarate-d5
    Monomethyl fumarate-d5 is deuterium labeled Monomethyl fumarate (HY-103252). Monomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF) (HY-17363), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease.
    Monomethyl fumarate-d<sub>5</sub>
  • HY-113629R
    2-Keto-D-Glucose (Standard)
    Cefixime (trihydrate) (Standard) is the analytical standard of Cefixime (trihydrate). This product is intended for research and analytical applications. Cefixime trihydrate (FR-17027 trihydrate) is an antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections.
    2-Keto-D-Glucose (Standard)
  • HY-106714R
    Clocortolone pivalate (Standard)
    Clocortolone pivalate (Standard) is the analytical standard of Clocortolone pivalate. This product is intended for research and analytical applications. Clocortolone pivalate is a synthetic glucocorticoid corticosteroid and corticosteroid ester. Clocortolone pivalate is indicated for seborrheic dermatitis, contact dermatitis, atopic dermatitis and psoriasis.
    Clocortolone pivalate (Standard)
  • HY-131936
    Diazoxon
    Diazoxon is a metabolite of Diazinon (HY-B1113). Diazinon is an organophosphate insecticide.
    Diazoxon
  • HY-12365S2
    Tauro-obeticholic acid-d5
    Tauro-obeticholic acid-d5 is deuterium labeled Tauro-obeticholic acid (HY-135399). Tauro-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist.
    Tauro-obeticholic acid-d<sub>5</sub>
  • HY-100599R
    Urolithin A (Standard)
    Atractylodin (Standard) is the analytical standard of Atractylodin. This product is intended for research and analytical applications. Atractylodin (Atractydin) is an orally active active ingredient obtained from the rhizome of Atractylodes lancea and A. chinensis. Atractylodin is a natural insecticide. Atractylodin has anti-inflammatory activity.
    Urolithin A (Standard)
  • HY-149466
    Moxifloxacin N-sulfate
    		Antagonist
    Moxifloxacin N-sulfate is a metabolite of moxifloxacin (HY-66011A).
    Moxifloxacin N-sulfate
  • HY-177337
    N-Didesmethyladitoprim
    N-Didesmethyladitoprim is a metabolite of Aditoprime (HY-139743). Aditoprime is a selective bacterial dihydrofolate reductase (DHFR) inhibitor with IC50s of 47 and 520 nM for E.coli and L.casei DHFR , respectively. Aditoprime inhibits the transformation of dihydrofolic acid to tetrahydrofolic acid. Aditoprime has a broad-spectrum antibacterial activity and excellent pharmacokinetics.
    N-Didesmethyladitoprim
Cat. No. Product Name / Synonyms Application Reactivity